thyroid hormone receptor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12073	ML-109		TSH Receptor
	ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)		TSH Receptor
T12192	NCGC00229600		Others , TSH Receptor
	NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.		Others , TSH Receptor
T5360	Eprotirome	KB2115	Thyroid hormone receptor(THR)
	Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.		Thyroid hormone receptor(THR)
T40548	NH-3		Thyroid hormone receptor(THR)
	NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...		Thyroid hormone receptor(THR)
T1604	Tiratricol	3,3',5-Triiodothyroacetic acid	Thyroid hormone receptor(THR)
	Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of A...		Thyroid hormone receptor(THR)
T5383	D3-βArr	NCGC00379308	TSH Receptor
	D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.		TSH Receptor
T6956	Protirelin	Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T13072	Taltirelin acetate	TA-0910 acetate	Thyroid hormone receptor(THR)
	Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).		Thyroid hormone receptor(THR)
T3595	Resmetirom	VIA-3196,MGL3196	Thyroid hormone receptor(THR)
	Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.		Thyroid hormone receptor(THR)
T5313	Sobetirome	IACS-010759,QRX-431	Thyroid hormone receptor(THR)
	Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).		Thyroid hormone receptor(THR)
T13492	3,5-Diiodothyropropionic acid	C082182,Ditpa cpd	Thyroid hormone receptor(THR)
	3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).		Thyroid hormone receptor(THR)
T7578	REVERSE T3	3,3',5'-triiodo-L-thyronine	Thyroid hormone receptor(THR)
	Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.		Thyroid hormone receptor(THR)
TP1022	Protirelin Acetate	TSH-RF Acetate,TRH Acetate,TRF Acetate	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T1669	Liothyronine sodium	3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel	Thyroid hormone receptor(THR)
	Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine s...		Thyroid hormone receptor(THR)
T0864	L-Thyroxine	Levothyroxine,NSC 36397,T4	Thyroid hormone receptor(THR) , Endogenous Metabolite
	L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in...		Thyroid hormone receptor(THR) , Endogenous Metabolite
T1653	Liothyronine	Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T22355	L-Thyroxine sodium	LT4 sodium,Levothyroxine sodium,L-T4 sodium	Thyroid hormone receptor(THR)
	L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.		Thyroid hormone receptor(THR)
T16442	PCO371	2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...		Thyroid hormone receptor(THR)
T7590	Taltirelin	TA-0910	Thyroid hormone receptor(THR)
	Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1].		Thyroid hormone receptor(THR)
T15699	L-Thyroxine sodium salt pentahydrate	Sodium levothyroxine pentahydrate,Levothyroxine	Thyroid hormone receptor(THR)
	L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine, is a synthetic hormone utilized in the study of hypothyroidism. It is biologically activated into Triiodothyronine (T3) from its original form, L-Thyroxi...		Thyroid hormone receptor(THR)